
Polynucleotides for the Face
Regenerative skin treatment for crepey wrinkles and declining skin quality, for more freshness and glow – at Derma Medical Clinic in Zurich Sihlcity.
Polynucleotides for the Face
Polynucleotides for the Face at Derma Medical Clinic in Zurich – Sihlcity
Polynucleotides for declining skin quality on the face
When the skin becomes drier, fine lines develop or firmness declines, we can stimulate skin renewal with polynucleotides. These biostimulators strengthen the tissue and improve skin quality. Their lasting effect develops continuously over several weeks. The result: improvements in skin texture, elasticity and hydration, among other things, and a fresher, more radiant complexion.
Treatment Options
Procedure
Examinations
Duration
Socially presentable after treatment
Sports, Swimming, Sauna
Cost
Polynucleotides support skin regeneration
Polynucleotides are special biostimulators consisting of long chains of nucleotides, the building blocks of DNA. Medically prepared, they are introduced into the skin with fine needles. Polynucleotides support skin regeneration from within. As a result, the skin can retain more moisture, becomes denser and more elastic and looks more even and fresher overall.

Polynucleotides for different areas of the face
Fine lines often appear on the cheeks, around the mouth or in areas with thinning skin, such as the temples. With polynucleotides, we can also strengthen skin that is becoming more atrophic overall and showing first signs of ageing. Whether the entire face or only certain areas are included is decided on the basis of the skin analysis and your wishes.
Polynucleotides for the Face at a Glance
When an assessment makes sense
- For fine lines and crepey wrinkles
- For declining skin elasticity
- For thin and atrophic skin
- For an uneven skin texture
Examinations
- Medical assessment of skin quality
- Analysis of elasticity and skin thickness
- Analysis of wrinkle and tissue structure
- Discussion of contraindications
Therapeutic approaches
- Polynucleotides are introduced into the skin with fine needles.
- Several sessions a few weeks apart are usually required. The number and intervals depend on your skin condition.
Why Polynucleotides for the Face with Us?
Expert assessment of skin quality
Wrinkles and slack, rather dry skin can present in different ways. We discuss with you which changes matter most to you and whether polynucleotides are suitable for them.
Experienced Doctors
At Derma Medical Clinic, the treatment is carried out only by experienced specialists in aesthetic dermatology who specialise in regenerative injection treatments.
Modern Treatment Methods
Polynucleotides complement our range of modern treatments for improving skin quality. Other regenerative or device-based procedures are available depending on your skin.
Individual Consultation
We talk about what you would like for your skin and which treatment can achieve this. We also take possible combinations with other procedures into account.

Procedure
Initial consultation & diagnosis
The personal consultation first focuses on your skin and the changes that bother you. We then assess the skin texture, the degree of laxity, signs of ageing and the individual areas of the face.
Individual treatment planning
We determine which areas will be treated and how many sessions are required. The treatment protocol is based on the current condition of your skin and the result you want.
Treatment & support
Polynucleotides are injected into the skin in small quantities with fine needles. Small bumps or redness may appear immediately afterwards, which usually subside quickly.
Follow-up & adjustment
The complexion gradually improves over a period of several weeks. After the treatment series, we look at the result and discuss whether and when we recommend a touch-up.

Specialist experience with polynucleotides for the face
Polynucleotides are particularly suitable for declining skin quality, when the skin becomes thinner, drier or less elastic and fine lines develop. At Derma Medical Clinic, we use polynucleotides on the face, on the neck and around the eyes. The treatment is tailored to skin texture, region and personal wishes.
Dr. med. univ. Martina Tröbinger is a specialist in dermatology, venereology FMH and laser medicine FMCH. She specialises in medical aesthetic treatments. Her particular focus is on regenerative and skin-friendly treatments with natural results.

What you can expect from us
Long-term support
Skin quality improves over several weeks and usually lasts for several months. If required, touch-ups are possible at our practice to maintain or further improve the result.
Medicine and skin therapy under one roof
Our specialists also look at the skin from a dermatological perspective. The current skin condition and possible skin diseases are included in the treatment planning.
State-of-the-art therapies on site
In addition to polynucleotides, we offer other modern treatments to improve and rejuvenate skin texture. Each treatment is individually tailored to the skin findings.
More than just skin
In aesthetic treatments, we take skin quality, volume and individual facial proportions into account. To achieve natural results, we have to view the entire face as a unit. This is our standard at Derma Medical Clinic.
What patients say about our treatment
Improve your skin quality with polynucleotides.
For more hydration, elasticity, glow and a smoother skin texture. Individually planned and performed by a specialist.
FAQ
Frequently Asked Questions About Polynucleotides for the Face
What are polynucleotides?
Polynucleotides are special proteins with biostimulating properties. They can promote skin renewal and thus harmonise the complexion, even out an irregular skin surface, improve inflammation of the skin and strengthen the overall structure of the skin. After the treatment, the skin can retain more moisture, it becomes smoother and wrinkles soften.
What do polynucleotides do on the face?
Hydration, elasticity and thickness of the skin as well as skin texture can improve, and lines and fine wrinkles can look less pronounced. As the tissue regenerates, the skin often also looks fresher and more radiant. The change develops gradually.
Which skin is the treatment suitable for?
We use polynucleotides, for example, on thin skin with first signs of ageing or on less elastic skin, as well as for fine crepey wrinkles around the cheeks or mouth or an uneven skin texture.
When will I see first results?
The active ingredient stimulates skin regeneration, which takes several weeks. A first visible improvement in skin quality usually appears during the treatment series. How quickly the skin responds varies from person to person and also depends on the skin condition.
How many treatments are necessary?
Usually several sessions a few weeks apart. There is no generally applicable protocol. At Derma Medical Clinic, we plan the number and intervals together with you on the basis of the skin analysis.
How do polynucleotides differ from Profhilo?
Both procedures can improve skin quality. Profhilo is based on stabilised hyaluronic acid complexes. The focus is on hydration and smoothing the skin surface. Polynucleotides are DNA-based active ingredients with biostimulating properties. They are mainly used for regenerative skin treatments. Which treatment is more suitable depends on your skin condition and the desired result.
How do polynucleotides differ from hyaluronic fillers?
With hyaluronic fillers, we can replace lost volume or shape contours. Polynucleotides act directly on skin quality and are suitable for holistically strengthening and rejuvenating the skin.
What side effects can occur?
Slight swelling and bruising around the injection sites are possible. These reactions are usually only mild and temporary. On sensitive skin, they can be somewhat more pronounced. Overall, polynucleotides are well tolerated, and serious side effects are very rare when administered by a specialist. At Derma Medical Clinic, we provide comprehensive information about possible risks and side effects.
Can polynucleotides be combined with other treatments?
Depending on your skin condition, combinations are possible with botulinum toxin, Profhilo, PRP or device-based procedures, for example.







